PCCA _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016254
Fusion event
HBV-PCCA integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
401
End
436
Orient
+
Integrated sequence
CTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTT
Host Sequence
Chromosome
chr13
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
100901941/100249687 (Hg38)
End
100901976/100249722 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
PCCA
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-455-5p ; hsa-mir-7152-5p ; hsa-mir-568 ; hsa-mir-1273e ; hsa-mir-155-5p ; hsa-mir-4326 ; hsa-mir-15b-3p ; hsa-mir-486-5p
Nearest miRNA
hsa-mir-1297/Upstream/606538; hsa-mir-1267/Downstream/1717920;
Nearest TSS
ENST00000623511/Upstream/100486; ENST00000443601/Downstream/43502;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/160136, chr13-CpG: 51/Downstream/282420
Nearby gene
ZIC2(-262922) ; GGACT(+280476) ;
Upstream sequence
CACCAGCGCGTCGTAGCAGAGCCAGATGAgcgccccgcggtccgccgccccctgcccgcggcccaggcgcaggcccagggcgcagcccgccgccAGCAGC
Downstream sequence
acatttagattttcatccatttctttcgtcagagttttgtagttttcctcatagatacactgtatgtattttaagattcatgcctattttatttctttag
Target sequence
ttgaatcttcctatccatgtacattgattatctct
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate