Basic Information
VIS ID
TVIS10016256
Fusion event
HBV-LOC102724934 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1416
End
1451
Orient
-
Integrated sequence
CGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTG
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
29829454/29360248 (Hg38)
End
29829489/29360283 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC102724934
Nearest miRNA
hsa-mir-208a/Upstream/1726970; hsa-mir-1185-1/Downstream/1654363;
Nearest TSS
ENST00000550708/Upstream/381324; ENST00000549515/Downstream/30063;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/574385, chr14-CpG: 147/Downstream/566721
Upstream sequence
AAGGGATAGTGAAGGTTACTGACTTGCCTCTTGTGACTGTGCTAACATGTTGGCCAAGCTGGAGACCATGCTCAGTCATTTAGAGCTCAGTGTTTTCAAT
Downstream sequence
ATTAGTAACAGGAGGTATCTTACAGATGGATGGTGATAAAAAATTCCAATTTAAAATGAAAGTAGCAGCAATGCAAATTAGTGCAAAGTGGAACTTTTGT
Target sequence
TGAATCTCATATTAATGAGAGGATCCACATCAGAA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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