Fusion event
HBV-HS3ST4 integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
CTGCGCTGAACATGGAGAACATCACATCAGGATTCC
End
25918123/25906802 (Hg38)
Nearest miRNA
hsa-mir-1225/Upstream/1703536; hsa-mir-11401/Downstream/118435;
Upstream sequence
cgcggcagctcacgcctgtaatcccagcactttgggaggctgaggcgggtggatcacctgaggtcaggagttcaagatcagcctggccaacatggtgaaa
Downstream sequence
GCTTAAGGAAGGTAAAATTAAGTGGATTCCTAATAAACTGCCAACAATTTTAGATTTCAAGCAATAGAGAGACAGGATAAGATGCCTGTCTTGATTAAAG
Target sequence
GTGGCTGGTATCTAGGAAGCATGTTTGGAAATAGC
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.