ZNF771 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016264
Fusion event
HBV-ZNF771 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
443
End
478
Orient
-
Integrated sequence
TCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCC
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
30427577/30416256 (Hg38)
End
30427612/30416291 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNF771
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1225/Upstream/816991; hsa-mir-11401/Downstream/87628;
Nearest TSS
ENST00000527434/Upstream/8225; ENST00000562652/Downstream/12998;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/8305, chr16-CpG: 140/Downstream/1258
Upstream sequence
GAAAATAGGACAGACAGAACACACTAGAACTTAGTGTTGATAACTAGTTTGCTGAGCAAATTCATGAAGGTGTGAAAATACAAGACATGTATATGCCAAC
Downstream sequence
ttctcaattaacatctccagtctaggcctcgcttctgagctccagatatgtcaagaagccgtgacaccatccaaaacagatctcccctctcaacttgctc
Target sequence
ctcaaggctttataaaccatctataggttgacagc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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