Basic Information
VIS ID
TVIS10016267
Fusion event
HBV-chr17 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2861
End
3041
Orient
-
Integrated sequence
CTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGG
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
29236840/30909822 (Hg38)
End
29237030/30910012 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1180/Upstream/792650; hsa-mir-10226/Downstream/184338;
Nearest TSS
ENST00000595228/Upstream/3002; ENST00000580526/Downstream/11668;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/3302, chr17-CpG: 117/Downstream/11817
Nearby gene
TEFM(-2193) ;
Upstream sequence
tacatccacaaaaaagactgcaaagatgttcatggcagctttattactaacagctccaaactggaaacaacccaaatattcctcgacgtgggaacagata
Downstream sequence
tcccaagaagattgagaaacaatgttcacatttaaaaggaaaCAGGAggctgggcactgtggctcacgcctgtaatcccagcactttgggaggccaaggc
Target sequence
atctgaagctaaggaggagcactgagctggggtgtatgtttggaggccgtcagcctgtagagatggtactttactcatgagaacagatacgaggagccagggagagggggtaggcgtgagaaaagcacagtgagataaggagagaactccttgggagcaccaccattagatgtggttagaggattccgat
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate