Basic Information
VIS ID
TVIS10016271
Fusion event
HBV-chr19 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1094
End
1561
Orient
-
Integrated sequence
ACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTC
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
GRCh37/hg19
Start
23632979/23450177 (Hg38)
End
23633022/23450220 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10395/Upstream/3050823; hsa-let-7e/Downstream/11672480;
Nearest TSS
ENST00000633603/Upstream/34102; ENST00000531821/Downstream/206914;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/176111, chr19-CpG: 44/Downstream/20669
Nearby gene
ZNF91(-54753) ; ZNF675(+202685) ;
Upstream sequence
CCGTCACCACAGCAGATGCCTCCCCTGGAAAAAGCCCGGATTGCGGGCGTGGGTTCCTTGCCGCTGTCTGGGGTAGAGGAGAAGATGTTCAGCCTCCTCA
Downstream sequence
ggctgcatagtattctgtggtgtatatgtactacattttctgcatccagtctatcattgatgaacacgtgggttgatttaatgtatttgctattgtgaat
Target sequence
ttccatgtctaaaaaggacatgatcttggtttttttttttaat
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate