Basic Information
VIS ID
TVIS10016272
Fusion event
HBV-chr19 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1710
End
1732
Orient
-
Integrated sequence
CAAAGACTGTTTGTTTAAAGACT
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
GRCh37/hg19
Start
23633003/23450201 (Hg38)
End
23633096/23450294 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10395/Upstream/3050847; hsa-let-7e/Downstream/11672406;
Nearest TSS
ENST00000633603/Upstream/34126; ENST00000531821/Downstream/206840;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/176135, chr19-CpG: 44/Downstream/20595
Nearby gene
VN1R92P(-5012) ;
Upstream sequence
CAGTGGGCCGCACCAACCACCTCAGCCTGCCTCGATTCGCCCCTGTGGTCACCACTCCTGTTAAGGCCGAGGTGTCCCCTCACGGGGCTCCAGCTCTGAG
Downstream sequence
gatttaatgtatttgctattgtgaataggtctgcaatgaatgtgtgtgtgcatgtgtctttataatagaatgactttataatagaatgacatattcattt
Target sequence
cttggtttttttttttaatggctgcatagtattctgtggtgtatatgtactacattttctgcatccagtctatcattgatgaacacgtgggtt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate