VISDB Viral Integration Site DataBase

VIS ID

TVIS10016281

Fusion event

HBV-GLI2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

2941

Orient

-

Integrated sequence

TCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGA| |TTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTG

Chromosome

chr2

Cytoband

q14.2

Reference genome

Start

End

121642225/120884649 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-31-5p ; hsa-mir-218-5p ; hsa-mir-574-5p ; hsa-mir-5572 ; hsa-mir-4260 ; hsa-mir-450a-2-3p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-6740-5p ; hsa-mir-6867-5p ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-6747-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-4664-5p ; hsa-mir-342-5p ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-466 ; hsa-mir-6793-3p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-95-5p ; hsa-mir-223-5p ; hsa-mir-541-3p ; hsa-mir-654-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-92a-2-5p

Nearest miRNA

hsa-mir-1285-2/Upstream/7163281; hsa-mir-10b/Downstream/6538888;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/17015, chr2-CpG: 22/Downstream/99881

Nearby gene

LINC01101(-418300) ; TFCP2L1(+331938) ;

Nearest cancer related gene

GLI2(OG, No orient, 0)

Upstream sequence

aaaaaaaaaaaaaaaaaaaaagcaaaaaaGTAAGTAAATAAAATAGATTTTTTTAAAAAAGAAATAAGTATGTAAATAATGCAGGTTTCTATATCCTTAT

Downstream sequence

GGTTGAGACAGTGGATTTAATCAGGCTGGGTCCCCGCAGTTCACCCGCCCCTAAGCTGAGTGACATTAGGGTGGCCGTCGGAGTCCAGCTAGAGTGGGCA