hsa-mir-3691-3p _LIHC.png
PDE1A _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016287
Fusion event
HBV-PDE1A integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1720
End
1755
Orient
-
Integrated sequence
TTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATT
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
183058429/182193702 (Hg38)
End
183058464/182193737 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
PDE1A
miRNAs that regulate target gene
hsa-mir-133b ; hsa-mir-133a-3p ; hsa-mir-5587-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-3691-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-1264
Nearest miRNA
hsa-mir-10b/Upstream/888050; hsa-mir-1244-1/Downstream/2185238;
Nearest TSS
ENST00000437798/Upstream/90101; ENST00000469118/Downstream/48249;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/300910, chr2-CpG: 53/Downstream/522229
Upstream sequence
TTAGATATGGAAAGTAGAAATGCTGTGTGCTTATTTCCTGCTGGCTTGGGGAAGAGGGCAGTGCCTAGGTCTGTCTATAACCaaaaaaaaaaaaaaaaaa
Downstream sequence
TTATAAATATTTTATGGAATATTAGAACCCCTGGTGTAATCGGTGTTTATAGTACTTTTATGGCTCTTGAAACTAAAAGCTTTACTTTTTTACATTTAAA
Target sequence
AATATTGGTCTGATATAACTATATTTCTGTGAATG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate