Basic Information
VIS ID
TVIS10016289
Fusion event
HBV-chr2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1746
Orient
-
Integrated sequence
AGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGG| |GGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCT
Host Sequence
Chromosome
chr2
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
194448269/193583544 (Hg38)
End
194448269/193583544 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10b/Upstream/4450433; hsa-mir-1244-1/Downstream/13199690;
Nearest TSS
ENST00000437798/Upstream/833577; ENST00000569293/Downstream/314823;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1387458, chr2-CpG: 150/Downstream/2073287
Nearby gene
PCGEM1(-806644) ; SLC39A10(+2073262) ;
Upstream sequence
TGCTCTCGTCTCTAGCCTGTACTCACCTGGCTTCATCTCCTCTCAGCTCAGCCCTCTGGCCAGCCCCTGCTCATTGTTTAGAACTATCAAATAGCACTCG
Downstream sequence
tgtgctatctcctgtcattggactggagtgggaggacagttgctgaagccatggtttatcttgggcagggtgatttgtggccaggagaaacagctttgtg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate