VISDB Viral Integration Site DataBase

VIS ID

TVIS10016293

Fusion event

HBV-CYP20A1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1497

End

1765

Orient

-

Integrated sequence

TCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGA

Chromosome

chr2

Cytoband

q33.2

Reference genome

Start

End

204105276/203240553 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-1-3p ; hsa-mir-24-3p ; hsa-mir-203a-3p ; hsa-mir-526b-5p ; hsa-mir-24-2-5p ; hsa-mir-24-1-5p ; hsa-mir-4635 ; hsa-mir-6516-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6807-5p ; hsa-mir-455-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4763-3p ; hsa-mir-650 ; hsa-mir-1207-5p ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-940 ; hsa-mir-3192-5p ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-7851-3p ; hsa-mir-490-3p ; hsa-mir-4307 ; hsa-mir-33a-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-6872-3p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-4535 ; hsa-mir-659-5p ; hsa-mir-6861-3p ; hsa-mir-492 ; hsa-mir-3663-5p ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-4638-3p ; hsa-mir-518c-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-514a-5p ; hsa-mir-8057 ; hsa-mir-106a-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-4284 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-3686 ; hsa-mir-6781-5p ; hsa-mir-3607-3p ; hsa-mir-615-3p ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-4743-5p ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-5693 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-383-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-4695-5p ; hsa-mir-6749-3p ; hsa-mir-4764-3p ; hsa-mir-1910-5p ; hsa-mir-1264 ; hsa-mir-6750-3p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-1228-3p ; hsa-mir-7107-5p ; hsa-mir-3973 ; hsa-mir-1234-3p ; hsa-mir-1295b-3p ; hsa-mir-640 ; hsa-mir-324-5p ; hsa-mir-4733-5p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-377-3p ; hsa-mir-2276-3p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-7108-3p ; hsa-mir-4258 ; hsa-mir-6796-3p ; hsa-mir-498 ; hsa-mir-4279 ; hsa-mir-3157-5p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-1266-3p ; hsa-mir-25-3p ; hsa-mir-3160-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-4487 ; hsa-mir-495-5p ; hsa-mir-5186 ; hsa-mir-558 ; hsa-mir-6087 ; hsa-mir-92a-3p ; hsa-mir-92b-3p

Nearest miRNA

hsa-mir-10b/Upstream/14107086; hsa-mir-1244-1/Downstream/3542681;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/748, chr2-CpG: 73/Downstream/87379

Nearby gene

NBEAL1(-22203) ; ABI2(+88082) ;

Upstream sequence

CTCCTGACCTTCCCCCTCACACATTCTTTTCAGAAATGAAGCTGTGTGCAGGCTGTGAGGTGTCACTTCCCCCACGCTGGAGATATACAGCTTGGGCCTG

Downstream sequence

ttgttattttaaagtaggatggccaggagatacggagacatttgagtagaaacgcgaagaaggtgaaggtgcaagccattctgagaaagagcattctggg

Target sequence

CACCTTCTTAAATGTTCTTTTCCGAGCAGGTAAATGGATTAGACTAGAATCTTGCAACTACACAATCAGGGACTTCCTGAAATCTTATTTTCTGAGAAACTAAACAATTTTAGTGGTTCTTGAATTTTTGGTGATTTTAAAATGATACTCTTCTTTGATCAGCTCATAGAAGCACACtgtttattcttagcactagctatgtgccagatatggttccacgtgctgggaatccagccgtgaaacaaaccggacaga