VISDB Viral Integration Site DataBase

VIS ID

TVIS10016296

Fusion event

HBV-KLF7 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1142

End

1177

Orient

-

Integrated sequence

CTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGC

Chromosome

chr2

Cytoband

q33.3

Reference genome

Start

End

207975373/207110649 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-8085 ; hsa-mir-6878-5p ; hsa-mir-6731-5p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-6770-5p ; hsa-mir-4795-5p ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-3163 ; hsa-mir-1277-5p ; hsa-mir-410-3p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-186-3p ; hsa-mir-521 ; hsa-mir-8485 ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-4328 ; hsa-mir-324-5p ; hsa-mir-4733-5p ; hsa-mir-4789-3p ; hsa-mir-2681-5p ; hsa-mir-3156-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-188-3p ; hsa-mir-4301 ; hsa-mir-3977 ; hsa-mir-501-5p ; hsa-mir-6826-5p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-3177-5p ; hsa-mir-4257 ; hsa-mir-4797-5p ; hsa-mir-511-3p ; hsa-mir-574-5p ; hsa-mir-6867-5p

Nearest miRNA

hsa-mir-10b/Upstream/541; hsa-mir-1244-1/Downstream/55751;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/345178, chr2-CpG: 75/Downstream/55479

Upstream sequence

TGCCCTTAAAAATAAGAAACAATAAAATCGTATTATATCCATATCCCAGATCTCTCTAACCAATATTAAAAAGGATTTCTGCTGGTTGTATCAATGTACA

Downstream sequence

acgaatcttcaatctagaaggttaagcatttagtgGAGGTAGGGAGATTTCTTTCTTACCATAAGGGGAAAAGCGGCACATCATCTAAATCCTGACAGAA

Target sequence

aggggagggcatgaggctcaggaagagtcacaatc