Basic Information
VIS ID
TVIS10016297
Fusion event
HBV-LOC107985978 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1801
End
1823
Orient
-
Integrated sequence
TGCGCACCAGCACCATGCAACTT
Host Sequence
Chromosome
chr2
Cytoband
q34
Reference genome
GRCh37/hg19
Start
211898935/211034211 (Hg38)
End
211899009/211034285 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107985978
Nearest miRNA
hsa-mir-10b/Upstream/3279330; hsa-mir-1244-1/Downstream/1391978;
Nearest TSS
ENST00000437798/Upstream/362596; ENST00000434559/Downstream/631069;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/557399, chr2-CpG: 86/Downstream/1503171
Upstream sequence
ttaaataaggaaccaatagaacaaaaacaaatacagattaattaaacttcatcaaaattaaaaacttttgtgcttaaaaggacatcatttcaaagtaaaa
Downstream sequence
AGGGAATATTTTTGTAATTGCAGTATGCTCTATTGAATTTGGAGTATAGATTAATAGATTTTTCAGTAAATTTATTGTTATAACCAGTAAGCATTTTCAT
Target sequence
GTCAAGAACAGTGAAGATAAAAAATATGCACAAATAAAATACTATTTGTTGGTTCTGTATATAGGAAGAATGAA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate