Fusion event
HBV-FN1 integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
TTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCG
End
216296515/215431792 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1673460; hsa-mir-1244-1/Downstream/2468721;
Upstream sequence
TTCTTTTTCCACTTTTATGAAATTACAAAAACAAAGCCCAAAGCTCTTACCTGCACTGGCTTGGTGAAAGTCAGCTTCCTCCCCTGCCCCATCAATAGCA
Downstream sequence
TAAGCATCCCAGCTCTTGCTCAGCCCTAAGACTCACACACCTATGGGCTTGCAGGTCCATTCTCCTTTTCCATTACCAAGACACACACACTCTAACATGT
Target sequence
GTTAAGACTTCTATGTGTAGTCAGTACTTTTTGATCTAACTCCTGTAAGAAGACTATGGATTATATAATAATTCATTATTTCAAACAAAATTCCCATTTCTTTATTGGTTTTCACTGGAATTCAGGTCTATGACCTATGTAGATGTGATTCTGGTCCAACCCCACATTAGAAC
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.