Basic Information
VIS ID
TVIS10016307
Fusion event
HBV-chr20 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2881
End
2916
Orient
-
Integrated sequence
GGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTT
Host Sequence
Chromosome
chr20
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
21515378/21534740 (Hg38)
End
21515413/21534775 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-103a-2/Upstream/3064049; hsa-mir-1-1/Downstream/4673411;
Nearest TSS
ENST00000382410/Upstream/4538; ENST00000622928/Downstream/35201;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/11447, chr20-CpG: 50/Downstream/168331
Upstream sequence
TTCATTTGTGGATTGTGACGCTGGCTCAGCCTGTGCTTGGGCTCCACTGCAGAGTTGCGCGGCTGGTGGAGGCTTGTGCTCAGGTTGTAATAAAGCAATA
Downstream sequence
TGGCAAGCTGAACTGTCAAGGACAATATGTAGACTATTGCAGTTAAACAGGGGATTGTGTCTCCCAAGAAAGGATTCCACCATCTCGGTGGAGTTAAGTA
Target sequence
CCCCGGTGCTATTGTTATTTTACAGTCTGGCTGAA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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