NAPB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016308
Fusion event
HBV-NAPB integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
767
End
802
Orient
+
Integrated sequence
TCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTT
Host Sequence
Chromosome
chr20
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
23375394/23394757 (Hg38)
End
23375429/23394792 (Hg38)
Orient
+
Location type
Intronic
Target gene
NAPB
miRNAs that regulate target gene
hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/4924066; hsa-mir-1-1/Downstream/2813394;
Nearest TSS
ENST00000382410/Upstream/25886; ENST00000619238/Downstream/26622;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/28744, chr20-CpG: 99/Downstream/25679
Nearby gene
GZF1(-21746) ; CSTL1(+44892) ;
Upstream sequence
tgcatgtgtgcatacagctatgcacattgtgtgtacatgcacattgtgtgtacatgtgtatatttcaggatgtgcatatgtgtaaaagttgtgtacatgt
Downstream sequence
GAAAGTCTCCAGGCAAGGCCATCTATGACCACTCTACACCTACGATCACTCTCAGACTGAGGAGAGGAGAGTTCTTTGAGTCAGCTTATCTGCCTGCTTC
Target sequence
agcccatctacttagccaGCTAGTAGACTTTGCCA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate