Basic Information
VIS ID
TVIS10016311
Fusion event
HBV-LOC107986011 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
974
End
1009
Orient
-
Integrated sequence
ATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTT
Host Sequence
Chromosome
chr3
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
24551443/24509952 (Hg38)
End
24551478/24509987 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3A
Target gene
LOC107986011
Nearest miRNA
hsa-mir-12127/Upstream/4372311; hsa-let-7g/Downstream/1154886;
Nearest TSS
ENST00000440867/Upstream/10372; ENST00000455576/Downstream/177932;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/14007, chr3-CpG: 83/Downstream/11385
Upstream sequence
GCATGCCACTGACACAGCAGTTGGTGGTGGGTGCATGCAGGATGTCTGACTGCCCAAGGCTTGGCCTGTCCCTGCCCGCCTCCCTGCTGTGGCCCTAGCT
Downstream sequence
ctggcactctacaagcaatatctacccaggttggcacccatccattaatcaacTCAACACATTTTGGTATTGCCTGGTAAgcctggctagtccaatatct
Target sequence
gagaaagaattagacaaagccaaagacagaactct
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate