Basic Information
VIS ID
TVIS10016312
Fusion event
HBV-chr3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1564
End
1599
Orient
-
Integrated sequence
TCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCT
Host Sequence
Chromosome
chr3
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
35906736/35865244 (Hg38)
End
35906771/35865279 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12127/Upstream/120685; hsa-let-7g/Downstream/2104125;
Nearest TSS
ENST00000440867/Upstream/73067; ENST00000486143/Downstream/515065;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/225172, chr3-CpG: 50/Downstream/514931
Nearby gene
RPL36AP17(+6614) ;
Upstream sequence
ctgaattttgtgtggctgttacaaagTTAATTTTCCTGAAATTGGTTAAATTTTCAGAATAGAATTTTTTTTTTCATTTTCTTCAGATATGTCATCTATT
Downstream sequence
ATCACTAATAAGGTGATATGTTTCCAAAACCAACAGTTCTTgcgatagttttctgctacccaaatttagctaaggtgatttgtttctacaaattggcgca
Target sequence
ccaagaacctggacaccctccacaggtagcaCCAG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate