Basic Information
VIS ID
TVIS10016314
Fusion event
HBV-chr3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1649
End
1684
Orient
-
Integrated sequence
TCTTACATAAGAGGACTCTTGGACTCTCAGCAATGT
Host Sequence
Chromosome
chr3
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
94038696/94319852 (Hg38)
End
94038731/94319887 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7g/Upstream/7093575; hsa-mir-12124/Downstream/2040077;
Nearest TSS
ENST00000440867/Upstream/243510; ENST00000466089/Downstream/618285;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/256588, chr3-CpG: 41/Downstream/618001
Upstream sequence
gcaaagttttctagttaattttgctgcatcaatttttatcttcctaaaatttattctactctatgaggccaaagtgacattttaaaTATTTGAATTGAGG
Downstream sequence
tcatttcctgtagtcacatgacagatatggctgaaaaccacgcctaggatctgactgtaagggttgcagagttacagTATCAATTCAAAGCTTAATCTCC
Target sequence
TCAGAAATGTTCAagggcatctttgaggaagcctc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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