Basic Information
VIS ID
TVIS10016315
Fusion event
HBV-chr3 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1803
End
1825
Orient
+
Integrated sequence
CGCACCAGCACCATGCAACTTTT
Host Sequence
Chromosome
chr3
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
94038972/94320128 (Hg38)
End
94039095/94320251 (Hg38)
Orient
-
Nearest miRNA
hsa-let-7g/Upstream/7093851; hsa-mir-12124/Downstream/2039713;
Nearest TSS
ENST00000440867/Upstream/243786; ENST00000466089/Downstream/617921;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/256864, chr3-CpG: 41/Downstream/617637
Upstream sequence
TTTCTATCAGTGGATTGATTCCTTCTTTCTTGTACTAATGGTATATAGAAAATGTAAATGAATATTTTATTTAACTGCTATCATGGCATTGATCACATGT
Downstream sequence
tagcaggaatcaggataatgtataagattggattctatgggtgttagaccaaggaggatgaaaaacattgcttgattggacaatgttggataaaatgatt
Target sequence
atggctctcatgtctataatggaagttggatctcaacatggcacagatggagacattcaaggtctactctggaaaaatacaggttgtatgcccaaaggtttgtaggaccaccccagtttgtgt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate