Basic Information
VIS ID
TVIS10016316
Fusion event
HBV-chr3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1029
End
1064
Orient
+
Integrated sequence
TTACACAATGTGGTTATCCTGCGTTGATGCCTTTGT
Host Sequence
Chromosome
chr3
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
96395388/96676544 (Hg38)
End
96395423/96676579 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7g/Upstream/316505; hsa-mir-12124/Downstream/3287735;
Nearest TSS
ENST00000440867/Upstream/58308; ENST00000506569/Downstream/138002;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1738229, chr3-CpG: 49/Downstream/100194
Nearby gene
LINC00879(-1685254) ; EPHA6(+138001) ;
Upstream sequence
CAAGCAGGTGTTTCCATTAGAGCTTGCTCTAATAAACACATGCACACACACGTTCACACATAATATCTGACCGAGGGCAGAGTTAAACTTCCTGAGGCAC
Downstream sequence
tgtattttgcatcttcaaattgccagacctgggtgtaagattctgaggtccaaaggtaaataaattaaaccttcctatgtttgtaaggttaaaagtttga
Target sequence
AGAGCTAACTTTGGTAGTTTtttgctcatttaaca
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate