Basic Information
VIS ID
TVIS10016320
Fusion event
HBV-LINC00504 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1667
End
1702
Orient
-
Integrated sequence
TTGGACTCTCAGCAATGTCAACGACCGACCTTGAGG
Host Sequence
Chromosome
chr4
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
14737977/14736353 (Hg38)
End
14738012/14736388 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
LINC00504
Nearest miRNA
hsa-mir-12113/Upstream/1108396; hsa-mir-12115/Downstream/5791887;
Nearest TSS
ENST00000502981/Upstream/19758; ENST00000503926/Downstream/151779;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1108322, chr4-CpG: 31/Downstream/126496
Nearby gene
LINC01085(-596301) ; CPEB2(+266320) ;
Upstream sequence
CCTGATAAGAAGGACTTTCTGGATTACAAAGCCGAGGACCAGGCCTCACCAGGATGTTTTATGCACCTGGTTTTatttattcattcgttgaaaaattatc
Downstream sequence
cccttttcctgcttttcccatcatactccatgtcacaaaaccctggggtcctagtaaatctcatctctttactactttattactacacttgagttccagg
Target sequence
tattacatcaaaaccctagcttgctcactcggatc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate