Basic Information
VIS ID
TVIS10016324
Fusion event
HBV-LOC102723846 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1805
End
1828
Orient
+
Integrated sequence
CACCAGCACCATGCAACTTTTTCA
Host Sequence
Chromosome
chr4
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
32228536/32226914 (Hg38)
End
32228596/32226974 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
LOC102723846
Nearest miRNA
hsa-mir-12113/Upstream/3407246; hsa-mir-1243/Downstream/4199392;
Nearest TSS
ENST00000502981/Upstream/229517; ENST00000515181/Downstream/124064;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1503694, chr4-CpG: 100/Downstream/4017035
Upstream sequence
gccctctctcccacagcctctggatcctgggtatatctggccatccttgcagcgtggattctctgtgatcccacctttctgacatcactagcttcaaact
Downstream sequence
agacgaatatttctggttgtttccattattcaaatgagtaaaccttggcacagagggatgacaaggtatcacatcttagtaagtggtgaagactgggcaa
Target sequence
tggcaccaagccaattgctctacacatgataatttactttataatcacagcaaccctaaa
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate