ALB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016326
Fusion event
HBV-ALB integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1747
End
1769
Orient
-
Integrated sequence
GAGGAGATTAGGTTAAAGGTCTT
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
74270093/73404376 (Hg38)
End
74270202/73404485 (Hg38)
Orient
+
Location type
Intronic
Target gene
ALB
miRNAs that regulate target gene
hsa-mir-492
Nearest miRNA
hsa-mir-12113/Upstream/7127448; hsa-mir-1243/Downstream/3169083;
Nearest TSS
ENST00000502981/Upstream/68; ENST00000507673/Downstream/4153;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/144963, chr4-CpG: 20/Downstream/215842
Upstream sequence
gactaattaactgctcacatcactgctaccatttcccttcattcaggaagccttccctgacccAGGTCAATAAATGTCAGCTAGTGTGATGAATAATAAT
Downstream sequence
TAAAGAATTATTTTGGCATTTATTTCTAAAATGGCATAGTATTTTGTATTTGTGAAGTCTTACAAGGTTATCTTATTAATAAAATTCAAACATCCTAGGT
Target sequence
ATTCCAGGGGTGTGTTTCGTCGAGATGCACGTAAGAAATCCATTTTTCTATTGTTCAACTTTTATTCTATTTTCCCAGTAAAATAAAGTTTTAGTAAACTCTGCATCTT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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