Fusion event
HBV-ALB integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
GTTATGGGTCC
End
74283386/73417669 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/7140636; hsa-mir-1243/Downstream/3155899;
Upstream sequence
CCTTTGGGCACGTGTGTCATGCAGAAATTGGGGTTGTGCCAAAGTGTAGGTGAAAAGCCCAGGCAAGTACAGGACTTTGGTTGAAGCACTGCAACATGCC
Downstream sequence
GTGAGTCtttaaaaaaatataataaattaataatgaaaaaattttaCCTTTAGATATTGATAATGCTAGCTTTCATAAGCAGAAGGAAGTAAtgtgtgtg
Target sequence
GTGTCAACTCCAACTCTTGTAGAGGTCTCAAGAAACCTAGGAAAAGTGGGCAGCAAATGTTGTAAACATCCTGAAGCAAAAAGAATGCCCTGTGCAGAAGACTAT
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.