Fusion event
HBV-chr4 integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGA
End
100056186/99135035 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/137540; hsa-mir-1243/Downstream/2105760;
Upstream sequence
cagaaatttcccccaggtcctgggcaggtccagagatgctgcctgtgagccagggattggagtaaaaaaccttagaaacataccttatgttctattctac
Downstream sequence
ctggagctatcacaatgaacaacagagagttcttgccctcaaggaacaaatagtacaataggacaaaaaaataaatgggagatttctctatagtgtgata
Target sequence
aagctcctgttatgtgccagggacaattccaggct
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.