Basic Information
VIS ID
TVIS10016333
Fusion event
HBV-chr5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1679
End
1714
Orient
-
Integrated sequence
CAATGTCAACGACCGACCTTGAGGCATACTTCAAAG
Host Sequence
Chromosome
chr5
Cytoband
p15.32
Reference genome
GRCh37/hg19
Start
5524224/5524111 (Hg38)
End
5524259/5524146 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-4277/Upstream/3815243; hsa-mir-10397/Downstream/1303707;
Nearest TSS
ENST00000502646/Upstream/101369; ENST00000568962/Downstream/498137;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/28847, chr5-CpG: 37/Downstream/362803
Nearby gene
ICE1(-33921) ; LINC02145(+786294) ;
Upstream sequence
agtgggagattttaacaccccaccagcaatattagacagatcatcaagtcaaatcaggaatgtaatctcattcacaattgccacaaaaagaataaaatac
Downstream sequence
CCCATTCTTCACAGTGAccttctcctggaccttgattcagcctcagaagctttctcaacacagtaccaagagattaaatttggcacaggatgtaaatttg
Target sequence
AAACGCACAAGCCCTGTGCTGTGGCTGTGGCTGAC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate