Basic Information
VIS ID
TVIS10016337
Fusion event
HBV-chr5 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1806
End
1826
Orient
-
Integrated sequence
ACCAGCACCATGCAACTTTTT
Host Sequence
Chromosome
chr5
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
67420480/68124652 (Hg38)
End
67420740/68124912 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10397/Upstream/8420949; hsa-mir-103a-1/Downstream/4044555;
Nearest TSS
ENST00000502646/Upstream/222052; ENST00000520762/Downstream/64964;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/960885, chr5-CpG: 159/Downstream/90132
Upstream sequence
gctcacaccaagccgccctcagccccctactcagtctccctcccatacttggtgttcaaagtccagacggggctgaagaggcagggagcaggcatgtcag
Downstream sequence
aaaacaattttaaaattcttatgcaaccaaaaaagagcctgagtagccgaggcattcctaagcaaaaagaacaaagctgaaggcaacacactacctgatt
Target sequence
aatgtaatctcattcacaattgccacaaaaagaataaaataccaggaatacagctaatgagggaggtgaaaaggctctgcaaggtgaactacaaaacactgctcaaagaaatcagagatgacccaaacaattggaaaaacattccatgctcatggataggaagaatcaatattattaaaatgaccatactacccaaagcaatttatagattcaatgctattcataatgaactaccattgacattcttcacagaac
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate