Fusion event
HBV-EPB41L4A integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
ATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCT
End
111477810/112142113 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10397/Upstream/1628163; hsa-mir-103a-1/Downstream/4113630;
Upstream sequence
gtggaataggtagagagttgcccacagtggtctggaaaagagaagaggactgaccaggtgacccaaattttacctgaggcatcctcctggaaaaattctg
Downstream sequence
TTGGAGAAGGCTGGCTCTGGGATATGCACAGAGCCTTATACACTAGGTTCTAAGACTCCTCAACTTAAATAATAGCCACTTACCACTACTCCTCTCCTTC
Target sequence
TCTCTCTTCCCCATATTTTACCCTTTTGAGTTTCT
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.