Basic Information
VIS ID
TVIS10016345
Fusion event
HBV-chr5 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1787
End
1809
Orient
+
Integrated sequence
GGCATAAATTGGTCTGCGCACCA
Host Sequence
Chromosome
chr5
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
150629164/151249603 (Hg38)
End
150629237/151249676 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10397/Upstream/1516713; hsa-mir-103a-1/Downstream/272411;
Nearest TSS
ENST00000502646/Upstream/25458; ENST00000523004/Downstream/3216;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/25411, chr5-CpG: 21/Downstream/3195
Nearby gene
GM2A(+3449) ;
Upstream sequence
GGAGCACTGCTTCGGGACCAAACTGCCCCCCAAGAgttcgtggtttgtttccccaaccagattctaagatcatggaaaacagagaactttattgtacttt
Downstream sequence
ggtctggaaaagagaagaggactgaccaggtgacccaaattttacctgaggcatcctcctggaaaaattctgggcccagactggggtccctgggagcatc
Target sequence
caaattgatcgcaatggtggaggacgtagccgagcggggaatcaggtggaataggtagagagttgcccacagt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate