Basic Information
VIS ID
TVIS10016346
Fusion event
HBV-chr5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2946
End
2981
Orient
+
Integrated sequence
ACTTCAATCCCAACAAGGACACCTGGCCAGACGCCA
Host Sequence
Chromosome
chr5
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
150629309/151249748 (Hg38)
End
150629344/151249783 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10397/Upstream/1516858; hsa-mir-103a-1/Downstream/272304;
Nearest TSS
ENST00000502646/Upstream/25603; ENST00000523004/Downstream/3109;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/25556, chr5-CpG: 21/Downstream/3088
Nearby gene
GM2A(+3304) ;
Upstream sequence
agaatgcaattgggaagggacacactaagagaagagggattctcaggtggtaactgcaagtgttcacattaatttttaaaaccatgcatttatattttat
Downstream sequence
tagggccctgacttagcctgttagatgtctctgaccttagataggtgcaggcattgctttggaatggttccctccaccactgaagacctactgtgaactt
Target sequence
ggcccagactggggtccctgggagcatctccccat
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate