IP6K3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016349
Fusion event
HBV-IP6K3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
897
End
932
Orient
+
Integrated sequence
GTTATGGGTCCTTGCCACAAGAACACATCATACAAA
Host Sequence
Chromosome
chr6
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
33703432/33735655 (Hg38)
End
33703467/33735690 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
IP6K3
miRNAs that regulate target gene
hsa-mir-330-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p
Nearest miRNA
hsa-mir-1236/Upstream/37421; hsa-mir-10398/Downstream/163445;
Nearest TSS
ENST00000381078/Upstream/23928; ENST00000526556/Downstream/11158;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/23731, chr6-CpG: 32/Downstream/35938
Nearby gene
UQCC2(-23928) ; LEMD2(+35557) ;
Upstream sequence
tcctcaaatttaccttgcaTGTTATTATTTTCAAAAAAATCTTattgattcaatgcccacaaacatttgtggagtatttattatattgaagttactatat
Downstream sequence
GGGAGGTGGTGGCTGGGGCAGGGCAGCGCTTGGAAGGGCCCACACAGCCTCGACCCCAGAACAGGTTCCTCACTGGTACCTTAAACAGGACTGTAAATAT
Target sequence
CTGGAAAGCAGGGGAGGAAGGAGGAAGTTATATGA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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