VISDB Viral Integration Site DataBase

VIS ID

TVIS10016351

Fusion event

HBV-CD2AP integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

3131

End

3166

Orient

-

Integrated sequence

ACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCT

Chromosome

chr6

Cytoband

p12.3

Reference genome

Start

End

47509454/47541718 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-128-3p ; hsa-mir-124-3p ; hsa-mir-30b-5p ; hsa-mir-1-3p ; hsa-mir-19b-3p ; hsa-mir-484 ; hsa-mir-186-5p ; hsa-mir-92a-3p ; hsa-let-7a-5p ; hsa-mir-216a-3p ; hsa-mir-3681-3p ; hsa-mir-188-5p ; hsa-mir-491-3p ; hsa-mir-586 ; hsa-mir-548n ; hsa-mir-3148 ; hsa-mir-3688-3p ; hsa-mir-6073 ; hsa-mir-6083 ; hsa-mir-6866-3p ; hsa-mir-190a-3p ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-891b ; hsa-mir-4517 ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-6838-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-3606-5p ; hsa-mir-3607-3p ; hsa-mir-548ao-5p ; hsa-mir-5585-5p ; hsa-mir-548ax ; hsa-mir-551b-5p ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-6074 ; hsa-mir-625-3p ; hsa-mir-3182 ; hsa-mir-141-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428 ; hsa-mir-6124 ; hsa-mir-921 ; hsa-mir-6804-3p ; hsa-mir-3065-3p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-4477a ; hsa-mir-103b ; hsa-mir-664a-3p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-4797-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-548c-3p

Nearest miRNA

hsa-mir-10398/Upstream/2343913; hsa-mir-10524/Downstream/4602631;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/63328, chr6-CpG: 44/Downstream/526683

Upstream sequence

gtcttctttgtgatgtgtgctttcaactcaccgagataaagatttctcttgatagagcaatttggaaacactctttttgtagaatttgcaagggtaccct

Downstream sequence

agttccgcattgtaattttatggcccaggaaattgattcctagagaatttcagtgaaataactaggtaatgacaactgtacaagaacataagtcttctga

Target sequence

gaatgtcagagctgaggtaactgtagtggttttct