Basic Information
VIS ID
TVIS10016352
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
199
End
234
Orient
+
Integrated sequence
TACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCA
Host Sequence
Chromosome
chr6
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
48567012/48599276 (Hg38)
End
48567047/48599311 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10398/Upstream/3401506; hsa-mir-10524/Downstream/3545038;
Nearest TSS
ENST00000381078/Upstream/530587; ENST00000335783/Downstream/863880;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/530382, chr6-CpG: 20/Downstream/863910
Nearby gene
PTCHD4(-530622) ; MUT(+831025) ;
Upstream sequence
ccatgacaggcccccgtgtgtgatgttccccgccctgtgtccaagtgttctcattgttcaattcccacctatgagtgagaatatgtggtgtttggttttc
Downstream sequence
tggtcaggagaagttctcatctagaggctgcaggtaaaagatcgggttcaagctgactcttgctattggcagaattggtttccttggaactgtagaacta
Target sequence
atgatcagggtatcacaaagctaaaattcacgtat
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate