Basic Information
VIS ID
TVIS10016353
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
657
End
692
Orient
-
Integrated sequence
GCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTT
Host Sequence
Chromosome
chr6
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
87248283/86538565 (Hg38)
End
87248318/86538600 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10398/Upstream/7999256; hsa-mir-1202/Downstream/3774142;
Nearest TSS
ENST00000381078/Upstream/894773; ENST00000305344/Downstream/398706;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/859125, chr6-CpG: 43/Downstream/398935
Upstream sequence
tccctgcaaaggacattaactcatccttttttatggctgcatactattccatggtatatatgtgccacattttcttaatccagtctatcattgatggaca
Downstream sequence
tgataggttccagggattaggatgtgggcatctttggagggacttattcagtctaacacagagcctaagtgaattattcaacttcctgcatctggtccag
Target sequence
ctgcaaagcctcatttgtaatgtaaggtaacatat
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate