Basic Information
VIS ID
TVIS10016354
Fusion event
HBV-chr6 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1740
End
1761
Orient
+
Integrated sequence
GTTGGGGGAGGAGATTAGGTTA
Host Sequence
Chromosome
chr6
Cytoband
q16.1
Reference genome
GRCh37/hg19
Start
98890176/98442300 (Hg38)
End
98890247/98442371 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10398/Upstream/417679; hsa-mir-1202/Downstream/682238;
Nearest TSS
ENST00000381078/Upstream/227617; ENST00000328345/Downstream/390137;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1158977, chr6-CpG: 50/Downstream/382147
Upstream sequence
CTGTAATCCCTGGACCACACGGAACTCCCTCTCCTACATTTTTTTCAGCCCCACTGCGAGTTTGCGTCCGTGGTACTTTTAAGAGGGAGTCACTGCTGCC
Downstream sequence
ggcatcattacagttcactgcagcctcaacctccaaggctcaagccatcctcccatcacagcatccctagtagctgagactgtaggcatgcaccatcata
Target sequence
tttatattttattttattttattttttattttgtgacaaggtctcattctgtgctcaggctggggtgcaga
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate