Basic Information
VIS ID
TVIS10016355
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2591
End
2626
Orient
-
Integrated sequence
TTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGAT
Host Sequence
Chromosome
chr6
Cytoband
q16.1
Reference genome
GRCh37/hg19
Start
98895911/98448035 (Hg38)
End
98895946/98448070 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10398/Upstream/423414; hsa-mir-1202/Downstream/676539;
Nearest TSS
ENST00000381078/Upstream/233352; ENST00000328345/Downstream/384438;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1164712, chr6-CpG: 50/Downstream/376448
Nearby gene
MIR2113(-423416) ; POU3F2(+386668) ;
Upstream sequence
AGCCCTCTCTCTGCAGTAGAAAGAACCCTGAATGGAGAGAAGTCAGGCTGACTTTTAGCACTGACTGTGCATCTAGCCTAGATAACTTGATTTCCATTTG
Downstream sequence
cttatggatctaatatcttttcaaatatctctaaggataCTCTTTGGATATTTTCCCTATGTTTTAGGTTATCTTTTACTCCCTAAACTATCTGTTAACT
Target sequence
ttctgattatagctcatttccaacatttttattat
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate