Basic Information
VIS ID
TVIS10016357
Fusion event
HBV-chr7 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
745
End
780
Orient
-
Integrated sequence
TGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCT
Host Sequence
Chromosome
chr7
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
5127083/5087452 (Hg38)
End
5127118/5087487 (Hg38)
Orient
-
Fragile sites / regions
FRA7B
Nearest miRNA
hsa-mir-339/Upstream/298813; hsa-mir-10399/Downstream/408332;
Nearest TSS
ENST00000635602/Upstream/15327; ENST00000485854/Downstream/102701;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/3919, chr7-CpG: 40/Downstream/33655
Nearby gene
RBAK-RBAKDN(-14229) ; ZNF890P(+33857) ;
Upstream sequence
ctacattttattatgcacattttattaagtaataaataaTCAGAAAATATTcacccaccagatagcatagcctgcagcctcttaaataatagttataata
Downstream sequence
ggtacatggtcagcttctggtgagggtcctcttctgggttccagatcacagacttctagttgtgtcttcatgtggtggaaaaagagggagctctctgggg
Target sequence
tctcacaactctggagactgaagatctgagatcag
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate