Fusion event
HBV-CHN2 integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
GATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGT
End
29405166/29365550 (Hg38)
Nearest miRNA
hsa-mir-1183/Upstream/2195952; hsa-mir-10399/Downstream/315184;
Upstream sequence
cAGTCCtctttgtcttaaccttcacaaggaaactttgaaatgatacccactttttgttactgctttcctcaggccttttctgtctttaaaaccaacctct
Downstream sequence
aaggacatgatgataaggggcagataacaagaggtagagaaggaggagaggaagatgtcatagacagaaggaatagcatacgcaaaggccctgaggttga
Target sequence
aagaaagactccttcatgaagttgatatttgaact
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.