hsa-mir-5003-5p _LIHC.png
TNS3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016360
Fusion event
HBV-TNS3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
580
End
615
Orient
+
Integrated sequence
CTTCGGACGGAAATTGCACCTGTATTCCCATCCCAT
Host Sequence
Chromosome
chr7
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
47496142/47456544 (Hg38)
End
47496177/47456579 (Hg38)
Orient
-
Location type
Intronic
Target gene
TNS3
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-21-5p ; hsa-mir-342-3p ; hsa-let-7i-5p ; hsa-mir-8070 ; hsa-mir-5003-5p ; hsa-mir-8485 ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-1178-3p ; hsa-mir-6071 ; hsa-mir-6749-3p ; hsa-mir-377-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-5088-3p
Nearest miRNA
hsa-mir-1183/Upstream/2574744; hsa-mir-10399/Downstream/9499206;
Nearest TSS
ENST00000635602/Upstream/3313; ENST00000429010/Downstream/24706;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/201856, chr7-CpG: 95/Downstream/80132
Upstream sequence
aacaggagcgaaactccatcttaaaaaaaaaaaagaaaaaaaGAGACATATTCTTATAAATAACAGTTTTACCCACCATTCCCTTATATAAAAATGTGGC
Downstream sequence
GGAGGCCAGGAGGGCATCCATTCAGGATGTGAGGAGAAGGAAGACAAGGCCAACAGACCCAGGTCCCCTGAAGCTGAGGAGGTAAATGATGCTGAGACAG
Target sequence
TAGTATATTACATTATTACTATTGGGGCAATCAAC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate