Basic Information
VIS ID
TVIS10016363
Fusion event
HBV-chr7 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
600
End
608
Orient
+
Integrated sequence
TGTATTCCC
Host Sequence
Chromosome
chr7
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
109658084/110018027 (Hg38)
End
109658164/110018107 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10525/Upstream/7546496; hsa-mir-10399/Downstream/4635238;
Nearest TSS
ENST00000635602/Upstream/420861; ENST00000464835/Downstream/516647;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1447565, chr7-CpG: 68/Downstream/1543916
Upstream sequence
agattgtgccactgtactccagcctgggcaataagagtgagactttgtctcaaaaaagaaaaagaaTTTTTATTTGACTTCATGTAAACTGATTTCAAGT
Downstream sequence
AGTGattatttaatgttatttaattaattatttGGAAATATTACTTTTCCAAGATAAGTGATCAGCCAAGTCAACTGATTTCAAGACCCTTACCCTTCCC
Target sequence
GTGGCCAtttataaagtactttcaaataagtcatctcatttgatcttcataatgatgtaaaatatggcTTGTATTTTATT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate