Basic Information
VIS ID
TVIS10016365
Fusion event
HBV-chr7 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1817
End
1826
Orient
+
Integrated sequence
GCAACTTTTT
Host Sequence
Chromosome
chr7
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
109658149/110018092 (Hg38)
End
109658223/110018166 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10525/Upstream/7546561; hsa-mir-10399/Downstream/4635179;
Nearest TSS
ENST00000635602/Upstream/420926; ENST00000464835/Downstream/516588;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1447630, chr7-CpG: 68/Downstream/1543857
Upstream sequence
TACCACACAGAAGAGAATAGttagtatatgcaagcatataatcttcacacaaacacatttgtaacagacaaggaagacaataggcatagtcgccacagtc
Downstream sequence
GATCAGCCAAGTCAACTGATTTCAAGACCCTTACCCTTCCCAAGCTCCTATCAGTCTTTCTCTGGGAAGATAAGTATACCCATAGATGTTTAGCTATTTT
Target sequence
ggcTTGTATTTTATTAGTGattatttaatgttatttaattaattatttGGAAATATTACTTTTCCAAGATAAGT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate