EXOC4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016366
Fusion event
HBV-EXOC4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2258
End
2293
Orient
+
Integrated sequence
GGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGC
Host Sequence
Chromosome
chr7
Cytoband
q33
Reference genome
GRCh37/hg19
Start
132976529/133291775 (Hg38)
End
132976564/133291810 (Hg38)
Orient
+
Location type
Intronic
Target gene
EXOC4
miRNAs that regulate target gene
hsa-mir-33a-5p ; hsa-mir-877-3p ; hsa-mir-93-3p ; hsa-mir-3200-3p
Nearest miRNA
hsa-mir-10525/Upstream/787; hsa-mir-10399/Downstream/1915184;
Nearest TSS
ENST00000635602/Upstream/38410; ENST00000480840/Downstream/64577;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/209439, chr7-CpG: 17/Downstream/835442
Nearby gene
CHCHD3(-209736) ; LRGUK(+835540) ;
Upstream sequence
GGGCTGCATAGGTGTGCCAAGTTCCCCCAAGACTCATGCAGCATGGAAGCCCTGCCCTGGGAACCAGTGAACCTGGTAAGAACTTAGCAGAGACAACCAT
Downstream sequence
tatctttcttctatatagtctgttggctcaggctgtttattgaatcctttttctactgattcatgatgctattttggtcacacagcaacttatcacatat
Target sequence
atttttatatatggtattaactgaggatctaattt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate