Fusion event
HBV-chr8 integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTG
End
58299533/57386974 (Hg38)
Nearest miRNA
hsa-mir-124-1/Upstream/14490664; hsa-mir-10400/Downstream/4327814;
Upstream sequence
gtgaaaccctgtctctactaaaaatacagaaaattagctgggccatggtggtgcacatcctgtaatcttagttacttgggaggctgaagcatgagaatca
Downstream sequence
aatgaagaagctgattctaaaatttttgtgataatgcaaaggggctagaatagccaagcaattttgaagaagaacaaaattgaaagaatttcttaactgg
Target sequence
gcaaatccaataaaaaattccaggtattttgtaaa
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.