Basic Information
VIS ID
TVIS10016373
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
3195
End
3230
Orient
-
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
140182640/139170397 (Hg38)
End
140182675/139170432 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1204/Upstream/4365452; hsa-mir-10400/Downstream/1562132;
Nearest TSS
ENST00000518652/Upstream/42444; ENST00000518354/Downstream/292584;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/292193, chr8-CpG: 17/Downstream/448421
Nearby gene
COL22A1(-256404) ; KCNK9(+442163) ;
Upstream sequence
tggagactgggaagtccaagatcaagttgtcagcagatttggtgtctgataaaggtatcacagatggcgccttctcactgtgccctcacatgctgggagg
Downstream sequence
TGTTTTGGAGCTATATTCTGCATAGTTAACAAGGGTGTCCATTAAACATTATCTTGGACCTAATGGCCACTATTTCAATGCCTCAGCAGGATACTAAATG
Target sequence
AAACTAATACCCAAGAGCGACTGTGAATCAACAAT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate