Basic Information
VIS ID
TVIS10016379
Fusion event
HBV-LOC105373151 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2551
End
2586
Orient
-
Integrated sequence
ATACATTTACACCAAGACATTATCAAAAAATGTGAA
Host Sequence
Chromosome
chrX
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
28069267/28051150 (Hg38)
End
28069302/28051185 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105373151
Nearest miRNA
hsa-mir-23c/Upstream/8033963; hsa-let-7f-2/Downstream/444370;
Nearest TSS
ENST00000429181/Upstream/69701; ENST00000302196/Downstream/535210;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/187095, chrX-CpG: 30/Downstream/2195870
Nearby gene
DCAF8L1(-69701) ; IL1RAPL1(+536413) ;
Upstream sequence
GTGGGAGGCAGGCAGTGAATGGAGGCCTGAGTGATGGCAGCTAAAAGCATGGGTAACTGAAGGTCGGAGTCAATGACACATGAAGGACTAAGTGGATGAG
Downstream sequence
caaaatcagatttgtattcattaagctaagagataactgtgtgcaaagttataatcaaaattcgtaacattaaaataaaaattatcaatttgttttaatc
Target sequence
gatttcaagagcacaacatgaacaggtttgtcact
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate