Basic Information
VIS ID
TVIS10016382
Fusion event
HBV-chrX integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2962
End
2997
Orient
-
Integrated sequence
GGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGG
Host Sequence
Chromosome
chrX
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
63104641/63884761 (Hg38)
End
63104676/63884796 (Hg38)
Orient
-
Nearest miRNA
hsa-let-7f-2/Upstream/98674; hsa-mir-105-1/Downstream/2134074;
Nearest TSS
ENST00000429181/Upstream/75487; ENST00000617377/Downstream/320948;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/129423, chrX-CpG: 35/Downstream/159228
Nearby gene
MIR1468(-98674) ; AMER1(+300355) ;
Nearest cancer related gene
AMER1(TSG, +300355) ;
Upstream sequence
ATGAAATCCCATCTAcccaaaaggatcacccggggccactattttggttaatctgttgttgtctaggctcaggtctgcaggtctggtagctcagataatt
Downstream sequence
gagaggtgacagggacagcagtctagcctgtggggatctcctagaatttggcatggaaatggctgcaagggaacagaaacagggaatgcccatcctgtaa
Target sequence
ctcacatatatttgagttgatgggagagctacttg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate