APOOL _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016383
Fusion event
HBV-APOOL integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
3055
End
3090
Orient
+
Integrated sequence
GGCTCAGGGCATACTACAAACTTTGCCAGCAAATCC
Host Sequence
Chromosome
chrX
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
84305761/85050755 (Hg38)
End
84305796/85050790 (Hg38)
Orient
-
Location type
Intronic
Target gene
APOOL
miRNAs that regulate target gene
hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-3924 ; hsa-mir-376a-5p ; hsa-mir-5580-3p ; hsa-mir-4536-5p ; hsa-mir-4733-5p ; hsa-mir-4318 ; hsa-mir-200a-3p ; hsa-mir-141-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4746-3p
Nearest miRNA
hsa-let-7f-2/Upstream/824927; hsa-mir-105-1/Downstream/784990;
Nearest TSS
ENST00000429181/Upstream/4454; ENST00000443247/Downstream/58178;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/116170, chrX-CpG: 72/Downstream/192976
Nearby gene
UBE2DNL(-115865) ; SATL1(+41530) ;
Upstream sequence
CTCTCCCTTTAATATAAACTAGGAACATGATTATTTGAGAATGTTGGGGGTCACTTTCCTCTCCCAGTAAGATTGAGGAACCCTGGGTATTTTTACGTGT
Downstream sequence
aatttaaaggaaaacaaaatcctctgtgtttccatttcattccattcagaggttaccattaccctgaatttttactattattcccctcctttacttttta
Target sequence
gatgataatgatgtacaaccgtatacctagcaccc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate