Fusion event
HBV-chrX integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
TGTAGGCATAAATTGGTCTGCGC
End
126560819/127426838 (Hg38)
Nearest miRNA
hsa-let-7f-2/Upstream/6055557; hsa-mir-105-1/Downstream/6742540;
Upstream sequence
TAAGTTTTTCATTGTTCTTTTGTGTATGTTTGTTTTTATTAAATACTAATTAGAATCAAAAGGCTGTTCAAAatatgaaaggtatgaataataatatgat
Downstream sequence
tagcagcataggcagtagtaacttactacattataaattattttaaaggcacaggcaacatgatttgctgacagattttatatgaagcaaaatacaaaga
Target sequence
ggaattattgacatttgaagcaggtaattctgtgttgtatatgtcttgaggtgatcaagtgctctgtgcattgtaggatatttagcagaacttctgaccccccacccaccagaggccagtagcaaccctgcccctagttgtggcaactgaaaatgtctcccaacattgccaaatgtcctctggggcgaaaaatcaccttcagtagtcagaactgctggcccaggacaa
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.