Basic Information
VIS ID
TVIS10016388
Fusion event
HBV-chrX integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
846
End
881
Orient
-
Integrated sequence
AAACAAAGAGATGGGGTTACTCTCTAAATTTTATGG
Host Sequence
Chromosome
chrX
Cytoband
q25
Reference genome
GRCh37/hg19
Start
128334944/129200967 (Hg38)
End
128334979/129201002 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7f-2/Upstream/7829914; hsa-mir-105-1/Downstream/4968376;
Nearest TSS
ENST00000429181/Upstream/600499; ENST00000486673/Downstream/322244;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/2619629, chrX-CpG: 50/Downstream/321872
Nearby gene
ACTRT1(-1148597) ; SMARCA1(+245498) ;
Upstream sequence
gtggtcagagaatatacttgacatcatttcatttttttaaaattttttccaagactgcttttgtagtctaacatatggtttatccttgagaataatccac
Downstream sequence
CTTTTTCAGCCCATTACTGAACTAACTTCTGAGTTTCAAGACATCTTTTTCTTTTCTAAAAGGTGACCAGGAACATAGATTTCTGGGCCAGTCTAACAGG
Target sequence
TGCTAATGTAGACAGAAAGGGAAAAATCCACATTG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate